Description

Tetrahydro-2-Methyl-2H-Pyran-3,4-Diol is a versatile chiral diol building block, valued for its unique stereochemistry and functional group arrangement. This compound is essential for the synthesis of complex molecules, offering a rigid pyran ring structure that can impart specific conformational properties to target compounds. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for applications in asymmetric synthesis and as a precursor for advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides where specific stereochemistry is required for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis, such as in hydrogenation or oxidation reactions.
• Flavor and Fragrance Chemistry: Employed as a building block for synthetic musk compounds and other complex aroma chemicals.
• Polymer Modification: Acts as a monomer or cross-linking agent for creating specialty polymers with enhanced properties.
• Academic and Industrial Research: A valuable reagent for methodological development in organic synthesis and medicinal chemistry programs.

Basic Information

Product Name	Tetrahydro-2-Methyl-2H-Pyran-3,4-Diol
CAS No.	53951-42-1
Molecular Formula	C6H12O3
Molecular Weight	132.16 g/mol
Synonyms	3,4-Dihydroxy-2-methyltetrahydropyran; 2-Methyltetrahydro-2H-pyran-3,4-diol; (3R,4S)-3,4-Dihydroxy-2-methyltetrahydro-2H-pyran; (3S,4R)-3,4-Dihydroxy-2-methyltetrahydro-2H-pyran; 2-Methyl-3,4-dihydroxytetrahydropyran; Tetrahydro-2-methyl-3,4-pyrandiol; 2-Methyltetrahydropyran-3,4-diol
EINECS	Contact for details

Quality Control

Our Tetrahydro-2-Methyl-2H-Pyran-3,4-Diol is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment. We can support development projects with custom purity grades, from technical to research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (enantiomer excess)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.