Description

Propanedioic Acid, 1-[(1R,2S,5R)-5-Methyl-2-(1-Methylethyl)Cyclohexyl] Ester is a high-purity, chiral chemical intermediate of significant commercial interest. This compound is valued for its defined stereochemistry and functional group, which make it a versatile building block in advanced organic synthesis. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for the development of active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and production of active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring high stereochemical purity.
• Fine Chemical Synthesis: Used as a specialized building block in the multi-step synthesis of complex organic molecules, including flavors, fragrances, and agrochemicals.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the development and study of new asymmetric catalytic reactions.
• Material Science: Potential monomer or modifier in the synthesis of specialized polymers with tailored properties.
• Academic & Industrial R&D: Utilized in chemical research for method development and the exploration of new synthetic pathways.

Basic Information

Product Name	Propanedioic Acid, 1-[(1R,2S,5R)-5-Methyl-2-(1-Methylethyl)Cyclohexyl] Ester
CAS No.	53943-72-9
Molecular Formula	C15H26O4
Molecular Weight	270.37 g/mol
Synonyms	(1R,2S,5R)-Menthyl Hydrogen Malonate; (-)-Menthyl Hydrogen Malonate; L-Menthyl Hydrogen Malonate; (1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl Hydrogen Propanedioate; 1-[(1R,2S,5R)-5-Methyl-2-(propan-2-yl)cyclohexyl] Propanedioate; Menthyl Malonate Half Ester; 53943-72-9
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality management systems. Each batch is characterized using advanced analytical techniques including HPLC, GC, and chiral analysis to ensure high chemical and enantiomeric purity. A comprehensive Certificate of Analysis (COA) detailing identity, assay, impurity profile, and specific rotation is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed and stored upright. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.