Description

1-Oxa-4,7,10-Triazacyclododecane is a versatile macrocyclic polyamine ligand with a unique heteroatom-substituted structure. This compound is valued for its strong chelating properties and ability to form stable complexes with a wide range of metal ions, particularly transition metals. It is a critical intermediate and building block for researchers and manufacturers in the pharmaceutical, chemical synthesis, and materials science sectors, enabling applications from catalysis to medical imaging.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel macrocyclic drugs, including chemotherapeutic agents and diagnostic imaging contrast agents.
• Catalyst Ligand: Used as a chelating agent to create highly active and selective transition metal catalysts for organic synthesis and polymerization reactions.
• Chemical Research: Employed in academic and industrial R&D for developing new metal-organic frameworks (MOFs), supramolecular complexes, and functional materials.
• Analytical Chemistry: Functions as a complexing agent in separation sciences and sensor technologies for the detection and quantification of specific metal ions.
• Material Science: Incorporated into the design of advanced polymers, coatings, and nanomaterials where metal coordination is required for functionality.

Basic Information

Product Name	1-Oxa-4,7,10-Triazacyclododecane
CAS No.	53835-21-5
Molecular Formula	C8H19N3O
Molecular Weight	173.26 g/mol
Synonyms	1-Oxa-4,7,10-triazacyclododecane; 1,4,7,10-Tetraazacyclododecane, 1-oxa-; 1-Oxa-4,7,10-triazacyclododecane; 12-Membered ring oxa-triaza macrocycle; Oxa-Triaza Macrocyclic Ligand; 1-Oxa-4,7,10-triaza-cyclododecane; Aza-crown ether derivative
EINECS	Contact for details

Quality Control

Our 1-Oxa-4,7,10-Triazacyclododecane is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide full traceability and Certificates of Analysis (COA) are available for all shipments to ensure compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.