Description

6-o-(4-Methylphenylsulfonyl)-1,4-Anhydro-D-Mannitol 3,5-Bis(Methanesulfonate) is a specialized, high-purity chemical intermediate with a defined stereochemistry, primarily used in advanced synthetic organic chemistry. This compound matters for its role as a key building block in the synthesis of complex molecules, particularly in pharmaceutical research and development, where precise control over molecular structure is critical. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially those requiring complex carbohydrate or polyol-based scaffolds.
• Chiral Building Block: Utilized in asymmetric synthesis to introduce specific stereocenters into target molecules, leveraging its defined D-mannitol-derived configuration.
• Protecting Group Chemistry: The tosyl (4-methylphenylsulfonyl) and mesylate (methanesulfonate) groups can act as protective or activating groups in complex synthetic sequences.
• Agrochemical Research: Serves as an intermediate in the development of new pesticides or herbicides with specific modes of action.
• Academic & Institutional Research: Used in universities and research institutes for methodological studies in organic synthesis and carbohydrate chemistry.
• Process Chemistry Development: Investigated for scale-up and optimization in the production of specialty fine chemicals.

Basic Information

Product Name	6-o-(4-Methylphenylsulfonyl)-1,4-Anhydro-D-Mannitol 3,5-Bis(Methanesulfonate)
CAS No.	53691-34-2
Molecular Formula	C16H24O10S3
Molecular Weight	488.55 g/mol
Synonyms	1,4-Anhydro-6-O-(4-methylphenylsulfonyl)-D-mannitol 3,5-bis(methanesulfonate); 6-O-Tosyl-1,4-anhydro-D-mannitol 3,5-dimethanesulfonate; D-Mannitol, 1,4-anhydro-6-O-[(4-methylphenyl)sulfonyl]-, 3,5-bis(methanesulfonate); Tosylated Anhydromannitol Dimesylate; 1,4-Anhydro-6-O-p-tolylsulfonyl-D-mannitol 3,5-bis(methanesulfonate); 53691-34-2; Anhydro-D-mannitol derivative tosylate dimesylate.
EINECS	Contact for details

Quality Control

Our 6-o-(4-Methylphenylsulfonyl)-1,4-Anhydro-D-Mannitol 3,5-Bis(Methanesulfonate) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and chiral analysis to ensure stereochemical integrity. We provide comprehensive Certificates of Analysis (COA) detailing all specifications, ensuring traceability and compliance with research-grade material standards. Our quality commitment supports your development work from discovery through to scale-up.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.