Description

2(3H)-Furanone, Dihydro-4-(1-Methylethyl)-, (4S)- CAS NO 53657-15-1 is a chiral lactone compound, specifically the (4S)-enantiomer of dihydro-4-isopropylfuran-2(3H)-one. This compound matters as a versatile chiral building block and intermediate, prized for its defined stereochemistry which is critical for synthesizing optically active products. It is needed by research and development chemists in the pharmaceutical and agrochemical industries, as well as by manufacturers of fine chemicals and flavors & fragrances seeking to impart specific sensory or biological activity.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring specific stereochemical configurations.
• Agrochemical Synthesis: Used in the production of chiral pesticides, herbicides, and plant growth regulators where enantiomeric purity affects efficacy and environmental safety.
• Flavor & Fragrance Ingredient: Acts as a precursor for lactone-based flavor compounds, contributing to creamy, fatty, or fruity notes in advanced flavor formulations.
• Fine Chemical Research: Employed in academic and industrial R&D for exploring new synthetic methodologies and creating novel chiral molecules.
• Asymmetric Catalysis: Can be used as a substrate or ligand precursor in the development of asymmetric catalytic processes.

Basic Information

Item	Details
Product Name	2(3H)-Furanone, Dihydro-4-(1-Methylethyl)-, (4S)-
CAS No.	53657-15-1
Molecular Formula	C7H12O2
Molecular Weight	128.17 g/mol
Synonyms	(4S)-Dihydro-4-isopropylfuran-2(3H)-one; (S)-4-Isopropylbutyrolactone; (S)-4-Isopropyl-γ-butyrolactone; (S)-γ-Isopropyl-γ-butyrolactone; (S)-5-Methyl-4-propionyloxolan-2-one; L-(-)-4-Isopropylbutyrolactone; (4S)-4-(1-Methylethyl)dihydro-2(3H)-furanone
EINECS	Contact for details

Quality Control

Our 2(3H)-Furanone, Dihydro-4-(1-Methylethyl)-, (4S)- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high chemical and enantiomeric purity, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity (by GC/HPLC), chiral purity (by Chiral HPLC), and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C for long-term stability. This material is easily oxidized; ensure containers are properly sealed after each use to minimize exposure to air.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (4S)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.