Description

1-(2-Chloroethyl)-4-(Chloromethyl)Benzene is a versatile bifunctional aromatic intermediate featuring both chloroethyl and chloromethyl reactive sites. This compound matters for its utility in constructing complex molecular architectures, particularly in the synthesis of advanced pharmaceutical agents and specialty chemicals. Industries that require high-purity intermediates for research, development, and production, such as pharmaceutical, agrochemical, and fine chemical manufacturing, are the primary users of this material.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a benzyl-linked pharmacophore.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing specialized organic compounds used in electronic displays.
• Polymer & Resin Modifier: Employed to introduce reactive chloromethyl groups into polymer chains for cross-linking or functionalization.
• Cross-coupling Reactions: The chloromethyl group can be utilized in various palladium-catalyzed coupling reactions to form carbon-carbon bonds.
• Ligand & Catalyst Preparation: Acts as a precursor for synthesizing complex ligands used in homogeneous catalysis.
• Research & Development: A valuable reagent for medicinal chemistry and organic synthesis research in academic and industrial laboratories.
• Dye & Pigment Intermediate: Used in the synthesis of specialized colorants and functional dyes.

Basic Information

Product Name	1-(2-Chloroethyl)-4-(Chloromethyl)Benzene
CAS No.	53459-40-8
Molecular Formula	C9H10Cl2
Molecular Weight	189.08 g/mol
Synonyms	4-(Chloromethyl)phenethyl Chloride; 1-Chloro-2-[4-(chloromethyl)phenyl]ethane; p-(Chloromethyl)phenethyl Chloride; 4-(2-Chloroethyl)benzyl Chloride; α,α'-Dichloro-p-xylene (Note: This is a common but structurally related synonym); 1,4-Bis(chloromethyl)benzene derivative; (4-(Chloromethyl)phenyl)ethyl chloride; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We implement a multi-stage analytical protocol including chromatography and spectroscopy to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specific batch results are available upon request. Our quality management system is designed to meet the stringent requirements of cGMP and ISO standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption and potential decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Individual Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.