Description

4,4'-Dichloro-(1,1'-Biphenyl)-3-Ol is a specialized chlorinated biphenyl derivative with a phenolic hydroxyl group. This compound serves as a valuable advanced pharmaceutical intermediate and a versatile building block in organic synthesis. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those with biphenyl backbones.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and plant growth regulators.
• Liquid Crystal Materials: Used in research and production of liquid crystal displays (LCDs) due to its rigid, substituted biphenyl core.
• Polymer Chemistry: Monomer or modifier for engineering plastics and high-performance polymers requiring thermal and chemical stability.
• Organic Synthesis Reagent: Serves as a versatile intermediate for Suzuki coupling and other cross-coupling reactions to form complex biaryl systems.
• Research & Development: Critical compound for academic and industrial research in medicinal chemistry and material science.

Basic Information

Product Name	4,4'-Dichloro-(1,1'-Biphenyl)-3-Ol
CAS No.	53459-39-5
Molecular Formula	C₁₂H₈Cl₂O
Molecular Weight	239.10 g/mol
Synonyms	3-Hydroxy-4,4'-dichlorobiphenyl; 4,4'-Dichlorobiphenyl-3-ol; 3-Hydroxy-4,4'-dichloro-1,1'-biphenyl; 4,4'-Dichloro-3-biphenylol; Biphenyl-3-ol, 4,4'-dichloro-; (1,1'-Biphenyl)-3-ol, 4,4'-dichloro-
EINECS	Contact for details

Quality Control

Our 4,4'-Dichloro-(1,1'-Biphenyl)-3-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature and tendency for oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.