Description

1H-Imidazo[4,5-H]Quinazolin-6-Amine(9Ci) is a high-purity, specialized heterocyclic organic compound that serves as a critical building block in advanced chemical synthesis. This compound is valued for its unique fused-ring structure, which makes it a versatile intermediate for developing novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for lead optimization and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel kinase inhibitors, anticancer agents, and other biologically active heterocyclic compounds.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its complex nitrogen-containing scaffold.
• Material Science: Serves as a building block for organic semiconductors, ligands for metal-organic frameworks (MOFs), and other advanced functional materials.
• Academic & Contract Research: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.
• Chemical Biology: Utilized as a probe or scaffold in the design of enzyme inhibitors and molecular probes for biological target validation.

Basic Information

Product Name	1H-Imidazo[4,5-H]Quinazolin-6-Amine(9Ci)
CAS No.	53449-44-8
Molecular Formula	C9H7N5
Molecular Weight	185.19 g/mol
Synonyms	1H-Imidazo[4,5-h]quinazolin-6-amine; 6-Amino-1H-imidazo[4,5-h]quinazoline; Quinazolin-6-amine, 1H-imidazo[4,5-h]-; 53449-44-8; 1H-Imidazo[4,5-h]quinazoline-6-amine; Imidazo[4,5-h]quinazolin-6-amine; 6-Aminoimidazo[4,5-h]quinazoline
EINECS	Contact for details

Quality Control

Our 1H-Imidazo[4,5-H]Quinazolin-6-Amine(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.