Description

(-)-5,6,7,8-Tetrahydro-3,6,9-Trihydroxy-1-Methyl-8-Oxo-2-Anthracenecarboxylic Acid Methyl Ester is a high-purity, stereochemically defined anthracene derivative that serves as a critical chiral building block and reference standard in advanced organic synthesis. Its complex polycyclic structure with multiple functional groups makes it a valuable intermediate for pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require precise, high-quality intermediates for complex molecular construction.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for complex polycyclic target molecules.
• Reference Standard: Used as a high-purity analytical standard for quality control and method validation in pharmaceutical and chemical analysis laboratories.
• Organic Synthesis Building Block: Utilized in advanced organic chemistry for constructing complex anthracene-based frameworks due to its reactive hydroxyl, ketone, and ester functionalities.
• Biochemical Research: Employed in studies investigating molecular interactions, enzyme inhibition, or as a precursor for fluorescent probes or tags.
• Material Science Research: Potential precursor for the development of organic semiconductors or specialized dyes, leveraging its conjugated anthracene core.

Basic Information

Item	Details
Product Name	(-)-5,6,7,8-Tetrahydro-3,6,9-Trihydroxy-1-Methyl-8-Oxo-2-Anthracenecarboxylic Acid Methyl Ester
CAS No.	53254-81-2
Molecular Formula	C₁₈H₁₈O₇
Molecular Weight	346.33 g/mol
Synonyms	(-)-5,6,7,8-Tetrahydro-3,6,9-trihydroxy-1-methyl-8-oxoanthracene-2-carboxylic acid methyl ester; Methyl (1R,2S,3R,4S)-1,2,3,4-tetrahydro-1,4,7-trihydroxy-6-methyl-9,10-dioxo-2-anthracenecarboxylate; 1-Methyl-8-oxo-5,6,7,8-tetrahydro-3,6,9-trihydroxy-2-anthracenecarboxylic acid methyl ester; (-)-Tetrahydrotrihydroxymethyloxoanthracenecarboxylic acid methyl ester; 53254-81-2; Anthracene derivative, CAS 53254-81-2
EINECS	Contact for details

Quality Control

Our (-)-5,6,7,8-Tetrahydro-3,6,9-Trihydroxy-1-Methyl-8-Oxo-2-Anthracenecarboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and spectroscopic identification (IR, NMR). Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation. Keep the container tightly sealed when not in use to prevent moisture absorption.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.