Description

(1S,2R)‐Rel-2‐[(Benzyloxy)Carbonyl]Cyclopropane‐1‐Carboxylic Acid is a high-purity, chiral cyclopropane derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its rigid, strained cyclopropane ring and dual functional groups, which enable precise stereochemical control in the construction of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of protease inhibitors, antiviral agents, and other therapeutic molecules requiring specific stereochemistry.
• Agrochemical Research: Used in the development of novel pesticides and herbicides where the cyclopropane moiety contributes to biological activity and stability.
• Asymmetric Synthesis: Employed as a precursor for chiral ligands, catalysts, and auxiliaries in stereoselective chemical transformations.
• Peptidomimetics & Drug Design: The carboxylic acid and protected ester functionalities make it valuable for constructing conformationally restricted peptide analogs.
• Material Science: Investigated as a monomer or cross-linking agent for creating polymers with unique mechanical properties.
• Chemical Biology Probes: Utilized in the synthesis of labeled compounds and molecular probes for studying biological mechanisms.

Basic Information

Product Name	(1S,2R)‐Rel-2‐[(Benzyloxy)Carbonyl]Cyclopropane‐1‐Carboxylic Acid
CAS No.	53229-58-6
Molecular Formula	C12H12O4
Molecular Weight	220.22 g/mol
Synonyms	(1S,2R)-rel-2-(Benzyloxycarbonyl)cyclopropanecarboxylic Acid; 2-[(Benzyloxy)carbonyl]cyclopropanecarboxylic Acid, (1S,2R)-rel-; (1S,2R)-2-(Benzyloxycarbonyl)cyclopropane-1-carboxylic Acid; rel-(1S,2R)-2-(Benzyloxycarbonyl)cyclopropanecarboxylic Acid; Cyclopropane-1-carboxylic acid, 2-[(benzyloxy)carbonyl]-, (1S,2R)-rel-; Cbz-Protected Cyclopropane Amino Acid Derivative; N-Cbz-trans-1,2-cyclopropanedicarboxylic Acid Monoester
EINECS	Contact for details

Quality Control

Our (1S,2R)‐Rel-2‐[(Benzyloxy)Carbonyl]Cyclopropane‐1‐Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistent stereochemical integrity, meeting the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, chiral HPLC) and spectroscopic confirmation are provided to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de (for specified enantiomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.