Description

2'-o-Galloylhyperin is a specialized flavonoid glycoside compound, a derivative of hyperin (quercetin-3-O-galactoside) esterified with gallic acid. This unique molecular structure is valued for its potent biological activity, particularly as a key marker compound and active ingredient in botanical extracts. It is essential for research and development in the pharmaceutical, nutraceutical, and cosmeceutical industries, where standardized, high-purity natural compounds are required for efficacy and safety studies.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quality control and standardization of herbal medicines containing Hypericum perforatum (St. John's Wort) and related species.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a key intermediate or starting material in the synthesis of more complex therapeutic agents targeting inflammatory and neurological pathways.
• Nutraceutical Formulation: Incorporated into dietary supplements for its potential antioxidant and neuroprotective properties, contributing to product standardization and label claim verification.
• Cosmetic Actives: Utilized in advanced skincare formulations for its antioxidant capacity, helping to protect skin cells from oxidative stress and environmental damage.
• Biochemical Research: Employed in in-vitro and in-vivo studies to investigate mechanisms of action related to its anti-inflammatory, antiviral, and enzyme-inhibitory effects.
• Analytical Chemistry: Acts as a critical calibration standard in HPLC, LC-MS, and other chromatographic methods for the quantitative analysis of plant extracts and complex mixtures.

Basic Information

Product Name	2'-o-Galloylhyperin
CAS No.	53209-27-1
Molecular Formula	C28H24O16
Molecular Weight	616.48 g/mol
Synonyms	Quercetin 3-O-(2''-O-galloyl)-β-D-galactopyranoside; 2''-O-Galloylhyperin; Hyperin 2''-O-gallate; Quercetin 3-O-(2''-galloyl)-galactoside; 2'-O-Galloyl hyperin; 2''-O-Galloyl hyperoside; 2''-O-Galloylquercetin 3-galactoside
EINECS	Contact for details

Quality Control

Our 2'-o-Galloylhyperin is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We can supply material compliant with various pharmacopeial and internal specifications for reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment and handled under controlled conditions to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals (as Pb)	≤20 ppm
Solubility	Soluble in methanol, DMSO; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.