Description

3β-[(Trimethylsilyl)Oxy]Cholest-4-Ene is a high-purity, steroidal intermediate featuring a trimethylsilyl-protected hydroxyl group at the 3-beta position. This compound is a critical building block in the synthesis of complex steroid derivatives and other biologically active molecules, offering a protected functionality for selective chemical transformations. It is primarily utilized by research institutions and pharmaceutical companies engaged in advanced organic synthesis, drug discovery, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of novel steroid-based drugs and hormone analogs.
• Organic Synthesis Building Block: Used for the selective introduction of the cholestane skeleton or for further functionalization at other positions while protecting the 3-β-OH group.
• Biochemical Research: Serves as a precursor or standard in metabolic pathway studies and sterol biosynthesis research.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Material Science Research: Investigated as a precursor for liquid crystals or other advanced organic materials with specific steroidal frameworks.

Basic Information

Product Name	3β-[(Trimethylsilyl)Oxy]Cholest-4-Ene
CAS No.	53084-65-4
Molecular Formula	C₃₀H₅₄OSi
Molecular Weight	458.84 g/mol
Synonyms	Cholest-4-en-3β-ol trimethylsilyl ether; 3β-Trimethylsilyloxycholest-4-ene; 3β-(Trimethylsiloxy)cholest-4-ene; (3β)-Cholest-4-en-3-yl trimethylsilyl ether; 3-TMS-cholest-4-ene; 53084-65-4; 3β-TMS-cholest-4-ene
EINECS	Contact for details

Quality Control

Our 3β-[(Trimethylsilyl)Oxy]Cholest-4-Ene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality parameters. Our commitment to reliable supply and traceable documentation supports your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.