Description

2-Bromo-5-Methylaniline is a halogenated aromatic amine derivative, serving as a versatile and critical building block in advanced organic synthesis. Its molecular structure, featuring both a bromine substituent and an amino group on a methylated benzene ring, makes it a valuable intermediate for constructing complex molecules. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and pesticides, where its halogenated aniline structure contributes to biological activity.
• Dye and Pigment Manufacturing: Serves as a starting material for azo dyes and other complex colorants, leveraging the reactivity of its amino group.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and polymers due to its aromatic and electron-donating properties.
• Cross-Coupling Reactions: Acts as a substrate in Buchwald-Hartwig amination and other palladium-catalyzed coupling reactions to form carbon-nitrogen bonds.
• Chemical Research & Development: A standard reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating novel chemical entities.

Basic Information

Item	Details
Product Name	2-Bromo-5-Methylaniline
CAS No.	53078-35-6
Molecular Formula	C7H8BrN
Molecular Weight	186.05 g/mol
Synonyms	5-Amino-2-bromotoluene; 2-Bromo-5-methylbenzenamine; 2-Bromo-5-toluidine; 5-Methyl-2-bromoaniline; 1-Amino-2-bromo-5-methylbenzene; 2-Bromo-5-methyl-phenylamine; 2-Bromo-5-toluidine; Benzenamine, 2-bromo-5-methyl-
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Methylaniline is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming identity, assay, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	55 - 60 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.