Description

1-Acetoxy-17-Ethinyl-17-Hydroxy-18-Methyl-4-Estren-3-One is a high-purity synthetic steroid derivative of significant interest in advanced pharmaceutical research and development. This compound matters for its role as a key intermediate in the synthesis of novel therapeutic agents, particularly in the field of endocrinology and hormone-related therapies. It is primarily needed by pharmaceutical manufacturers, R&D laboratories, and fine chemical suppliers focused on producing active pharmaceutical ingredients (APIs) and reference standards.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of steroidal drugs and active pharmaceutical ingredients (APIs).
• Research & Development: Used in academic and industrial laboratories for pharmacological studies and the development of new therapeutic compounds.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Endocrine Research: Investigated for its biological activity and potential applications in hormone receptor modulation.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to create more complex, specialized steroid molecules.

Basic Information

Product Name	1-Acetoxy-17-Ethinyl-17-Hydroxy-18-Methyl-4-Estren-3-One
CAS No.	53020-96-5
Molecular Formula	C24H32O4
Molecular Weight	384.51 g/mol
Synonyms	17α-Ethynyl-17β-hydroxy-18-methyl-4-estren-3-one 1-acetate; 18-Methylnorethindrone Acetate; 17α-Ethynyl-18-methyl-19-nortestosterone 1-acetate; Tibolone Impurity; Tibolone Related Compound A; 1-Acetoxy-17α-ethynyl-17β-hydroxy-18-methylestr-4-en-3-one; 18-Methyl-17α-ethynyl-19-norandrost-4-en-17β-ol-3-one 1-acetate
EINECS	Contact for details

Quality Control

Our 1-Acetoxy-17-Ethinyl-17-Hydroxy-18-Methyl-4-Estren-3-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We adhere to cGMP principles where applicable to support its use in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.