Description

5-Butyl-5-Ethyl-1,3-Bis(trimethylsilyl)-2,4,6(1H,3H,5H)-pyrimidinetrione is a specialized organosilicon-protected derivative of a barbiturate core structure, offering unique reactivity and stability for advanced synthetic chemistry. This compound matters as a high-value building block and protecting group reagent, enabling precise molecular construction in sensitive applications where standard conditions are unsuitable. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key protected synthon in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of novel herbicides, insecticides, and fungicides that require the introduction of a functionalized heterocyclic moiety.
• Organometallic & Catalysis: Acts as a ligand precursor or a stabilizing agent in the preparation of metal-organic complexes for catalytic applications.
• Advanced Material Synthesis: Employed in the creation of specialty polymers, dendrimers, or organic electronic materials where silicon-based protecting groups are advantageous.
• Chemical Biology & Proteomics: Potential use as a probe or a tag in biochemical studies due to its silyl groups which can be selectively manipulated.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis, particularly in reactions requiring anhydrous and inert conditions.

Basic Information

Product Name	5-Butyl-5-Ethyl-1,3-Bis(trimethylsilyl)-2,4,6(1H,3H,5H)-pyrimidinetrione
CAS No.	52988-92-8
Molecular Formula	C₁₆H₃₂N₂O₃Si₂
Molecular Weight	356.61 g/mol
Synonyms	1,3-Bis(trimethylsilyl)-5-butyl-5-ethylbarbituric acid; 5-Butyl-5-ethyl-1,3-bis(trimethylsilyl)barbituric acid; 5-Ethyl-5-butyl-1,3-bis(trimethylsilyl)pyrimidine-2,4,6(1H,3H,5H)-trione; N,N'-Bis(trimethylsilyl)-5-ethyl-5-butylbarbituric acid; TMS-protected 5-ethyl-5-butylbarbituric acid; Barbituric acid, 5-butyl-5-ethyl-1,3-bis(trimethylsilyl)-; 52988-92-8
EINECS	Contact for details

Quality Control

Our production of 5-Butyl-5-Ethyl-1,3-Bis(trimethylsilyl)-2,4,6(1H,3H,5H)-pyrimidinetrione adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including NMR, HPLC, and GC, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.