Description

2,2-Dimethyltetrahydro-2H-Pyran-4-Carboxylic Acid is a versatile, functionalized heterocyclic building block. This compound is valued for its rigid, oxygen-containing pyran ring structure, which serves as a key intermediate in the synthesis of complex molecules. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for constructing novel active ingredients. Its specific stereochemistry and functional groups make it a critical precursor in medicinal chemistry and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drugs.
• Agrochemical Synthesis: Used as a building block for creating novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multi-step synthesis of complex flavors, fragrances, and advanced material precursors.
• Academic & Industrial Research: A valuable compound for methodological studies in organic synthesis, including ring-opening reactions and functional group transformations.

Basic Information

Product Name	2,2-Dimethyltetrahydro-2H-Pyran-4-Carboxylic Acid
CAS No.	52916-16-2
Molecular Formula	C8H14O3
Molecular Weight	158.20 g/mol
Synonyms	4-Carboxy-2,2-dimethyltetrahydropyran; 2,2-Dimethyl-4-carboxytetrahydropyran; 2,2-Dimethyltetrahydro-2H-pyran-4-carboxylic acid; Tetrahydro-2,2-dimethyl-4-pyrancarboxylic acid; 2,2-Dimethyltetrahydropyran-4-carboxylic acid; Dihydro-2,2-dimethyl-4H-pyran-4-carboxylic acid (tautomer); 52916-16-2; 2,2-Dimethyl-4-pyrancarboxylic acid, tetrahydro-
EINECS	Contact for details

Quality Control

Our 2,2-Dimethyltetrahydro-2H-Pyran-4-Carboxylic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with data from advanced techniques like HPLC, GC, and NMR. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.