Description

Pimaricin CAS NO 52882-37-8 is a polyene macrolide antifungal antibiotic produced by *Streptomyces natalensis*. This compound is highly valued for its potent activity against a broad spectrum of molds and yeasts, making it a critical preservative and antifungal agent. It is essential for industries requiring stringent microbial control, particularly in food preservation and pharmaceutical manufacturing.

Application

• Food & Beverage Preservation: Widely used as a natural preservative (E235) to prevent mold and yeast growth on the surface of cheese, sausages, and dried fruits.
• Pharmaceutical Formulations: Employed as an antifungal agent in topical creams, ointments, and ophthalmic solutions to treat fungal infections.
• Agricultural Applications: Used to control fungal diseases in post-harvest crops and as a feed additive to prevent mycotoxin formation.
• Research & Development: Serves as a selective agent in microbiological media and a tool compound in antifungal mechanism studies.
• Cosmetic Products: Incorporated into formulations to extend shelf life by inhibiting spoilage microorganisms.

Basic Information

Product Name	Pimaricin
CAS No.	52882-37-8
Molecular Formula	C33H47NO13
Molecular Weight	665.73 g/mol
Synonyms	Natamycin; Pimaricin; Tennecetin; Myprozine; Natacyn; CL 12625; Antibiotic A-5283; E235; (8E,14E,16E,18E,20E)-(1R,3S,5R,7R,12R,22R,24S,25R,26S)-22-[(3-Amino-3,6-dideoxy-β-D-mannopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-6,11,28-trioxatricyclo[22.3.1.05,7]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid
EINECS	258-156-9

Quality Control

Our Pimaricin is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for food-grade (FCC) and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, potency, and microbiological data is provided with every shipment to guarantee consistent quality and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to creamy-white powder
Identification (IR)	Conforms to standard
Assay (HPLC)	≥ 95.0%
pH (Suspension)	5.0 - 7.5
Loss on Drying	≤ 8.0%
Specific Rotation	+250° to +295°
Heavy Metals	≤ 20 ppm
Total Aerobic Microbial Count	≤ 100 cfu/g

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.