Description

2-(4-(Adamantan-1-yl)phenoxy)acetic acid is a high-value, functionalized organic compound featuring a rigid adamantane core linked to a carboxylic acid group via a phenoxyacetic acid spacer. This unique structure makes it a critical advanced pharmaceutical intermediate and a versatile building block in medicinal chemistry. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly those targeting central nervous system (CNS) disorders, antiviral agents, and anti-inflammatory compounds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its lipophilic adamantyl group which can enhance membrane permeability and metabolic stability.
• Agrochemical Synthesis: Serves as a precursor for developing new crop protection agents with potential fungicidal or herbicidal activity.
• Material Science: Acts as a monomer or cross-linking agent for creating high-performance polymers with specific thermal and mechanical properties.
• Ligand and Catalyst Development: The carboxylic acid functionality allows for coordination to metals, making it useful in designing new catalysts or metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying biological pathways and protein interactions.

Basic Information

Product Name	2-(4-(Adamantan-1-yl)phenoxy)acetic Acid
CAS No.	52804-26-9
Molecular Formula	C18H22O3
Molecular Weight	286.36 g/mol
Synonyms	2-[4-(1-Adamantyl)phenoxy]acetic Acid; 2-(p-Adamantylphenoxy)acetic Acid; 4-(1-Adamantyl)phenoxyacetic Acid; Acetic acid, 2-[4-(tricyclo[3.3.1.13,7]dec-1-yl)phenoxy]-; NSC 339586; Adamantylphenoxyacetic Acid; p-Adamantylphenoxyacetic Acid
EINECS	Contact for details

Quality Control

Our 2-(4-(Adamantan-1-yl)phenoxy)acetic acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.