Description

2-(Benzyloxy)-5-Chlorobenzoic Acid is a versatile benzoic acid derivative characterized by its benzyl-protected phenolic oxygen and chlorinated aromatic ring. This compound matters as a critical synthetic intermediate, offering a reactive carboxylic acid group and a protected phenol moiety for constructing complex molecules in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and agrochemical industries for use in multi-step organic synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a chlorinated benzyl-protected phenolic scaffold.
• Agrochemical Synthesis: Used in the research and development of herbicides, fungicides, and other crop protection agents where its specific substitution pattern is advantageous.
• Ligand and Catalyst Preparation: Acts as a precursor for synthesizing specialized ligands used in metal-catalyzed coupling reactions and other catalytic processes.
• Material Science Research: Employed in the development of advanced organic materials, such as monomers for polymers or components for liquid crystals.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry, including protection/deprotection strategies and cross-coupling reactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules on a commercial scale.

Basic Information

Product Name	2-(Benzyloxy)-5-Chlorobenzoic Acid
CAS No.	52803-75-5
Molecular Formula	C14H11ClO3
Molecular Weight	262.69 g/mol
Synonyms	5-Chloro-2-(phenylmethoxy)benzoic Acid; 5-Chloro-2-benzyloxybenzoic Acid; Benzoic acid, 5-chloro-2-(phenylmethoxy)-; 2-Benzyloxy-5-chlorobenzoic Acid; 2-(Benzyloxy)-5-chlorobenzoic acid; 2-(Phenylmethoxy)-5-chlorobenzoic Acid; 5-Chloro-2-(benzyloxy)benzoic Acid; 5-Chloro-salicylic acid benzyl ether
EINECS	Contact for details

Quality Control

Our 2-(Benzyloxy)-5-Chlorobenzoic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.