Description

(4R,4Ar)-Decahydro-4-Hydroxy-6α-(1-Hydroxy-1-Methylethyl)-4,8Aα-Dimethylnaphthalen-2-One is a high-purity, complex decalin-based ketone derivative valued for its unique stereochemistry and functional groups. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and fine chemical sectors for developing novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel therapeutic agents, particularly in steroid-like or terpenoid-based drug discovery.
• Agrochemical Synthesis: Used in the synthesis of advanced, biologically active molecules for crop protection and pest management products.
• Fine Chemical Production: Serves as a sophisticated building block for creating specialty chemicals, flavors, fragrances, and advanced materials.
• Academic & Industrial Research: A valuable reference standard and starting material for methodological studies in asymmetric synthesis and natural product chemistry.
• Catalyst & Ligand Development: Potential precursor for designing novel chiral ligands and organocatalysts used in enantioselective transformations.

Basic Information

Product Name	(4R,4Ar)-Decahydro-4-Hydroxy-6α-(1-Hydroxy-1-Methylethyl)-4,8Aα-Dimethylnaphthalen-2-One
CAS No.	52801-08-8
Molecular Formula	C15H26O3
Molecular Weight	254.37 g/mol
Synonyms	4-Hydroxy-6α-(1-hydroxy-1-methylethyl)-4,8aα-dimethyldecahydronaphthalen-2-one; (4R,4aR,6S,8aS)-4-(2-Hydroxypropan-2-yl)-6-hydroxy-4,8a-dimethyldecahydronaphthalen-2-one; Decahydro-4-hydroxy-6α-(1-hydroxy-1-methylethyl)-4,8aα-dimethylnaphthalen-2(1H)-one; A derivative of Sclareolide; Tetrahydro-2H-3a,6-epoxynaphth[2,1-b]oxepin-10(3aH)-one derivative
EINECS	Contact for details

Quality Control

Our (4R,4Ar)-Decahydro-4-Hydroxy-6α-(1-Hydroxy-1-Methylethyl)-4,8Aα-Dimethylnaphthalen-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets exacting research and process chemistry standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, prolonged storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal long-term stability. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% de
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.