Description

(S)-Quinuclidine-2-Carboxylic Acid Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate. This compound is valued for its rigid, bicyclic quinuclidine structure, which is instrumental in modulating the physicochemical and biological properties of target molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly in areas such as neurology and enzymology.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of drug candidates targeting various therapeutic areas.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and molecular recognition studies.
• Chemical Biology Probe Development: Serves as a core scaffold for designing probes to study enzyme function and receptor interactions.
• Asymmetric Catalysis Research: Employed as a precursor for chiral catalysts and auxiliaries in academic and industrial R&D.
• Reference Standard: Utilized as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(S)-Quinuclidine-2-Carboxylic Acid Hydrochloride
CAS No.	52730-01-5
Molecular Formula	C8H13NO2 • HCl
Molecular Weight	191.65 g/mol
Synonyms	(S)-1-Azabicyclo[2.2.2]octane-2-carboxylic acid hydrochloride; (2S)-Quinuclidine-2-carboxylic acid hydrochloride; L-Quinuclidine-2-carboxylic acid hydrochloride; (S)-2-Quinuclidinecarboxylic acid hydrochloride; (S)-Quinuclidinic acid hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-Quinuclidine-2-Carboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.