Description

(3S)-3A,5Aα,7,8,9,10,10Aβ,10Cα-Octahydro-3-Hydroxy-8β-Hydroxyacetyl-3Aα,8-Dimethyl-4H-3,10Bβ-Ethano-1H,3H-Benzo[H]Furo[4,3,2-De]-2-Benzopyran-4-One is a complex, high-purity organic compound with a defined stereochemistry, serving as a critical advanced intermediate in modern synthetic chemistry. Its intricate fused-ring structure makes it a valuable building block for the research and development of novel active pharmaceutical ingredients (APIs) and other fine chemicals. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used as a precursor in developing new-generation pesticides and herbicides with specific stereochemical activity.
• Academic & Institutional R&D: Serves as a model compound in methodological studies for novel organic synthesis routes, including catalytic asymmetric transformations.
• Process Chemistry Development: Employed in scaling up and optimizing synthetic pathways from laboratory to pilot plant scale for commercial production.
• Fine Chemical Synthesis: Acts as a building block for creating specialty chemicals used in materials science, such as liquid crystals or advanced polymers.

Basic Information

Item	Details
Product Name	(3S)-3A,5Aα,7,8,9,10,10Aβ,10Cα-Octahydro-3-Hydroxy-8β-Hydroxyacetyl-3Aα,8-Dimethyl-4H-3,10Bβ-Ethano-1H,3H-Benzo[H]Furo[4,3,2-De]-2-Benzopyran-4-One
CAS No.	52691-15-3
Molecular Formula	C21H26O6
Molecular Weight	374.43 g/mol
Synonyms	3-Hydroxy-8β-hydroxyacetyl-3aα,8-dimethyl-4H-3,10bβ-ethano-1H,3H-benzo[h]furo[4,3,2-de]-2-benzopyran-4-one; (3S)-3a,5aα,7,8,9,10,10aβ,10cα-Octahydro-3-hydroxy-8β-hydroxyacetyl-3aα,8-dimethyl-4H-3,10bβ-ethano-1H,3H-benzo[h]furo[4,3,2-de]-2-benzopyran-4-one; 52691-15-3; Benzo[h]furo[4,3,2-de]-2-benzopyran-4-one derivative; Fused-ring lactone intermediate; Chiral benzofurobenzopyranone.
EINECS	Contact for details

Quality Control

Our (3S)-3A,5Aα,7,8,9,10,10Aβ,10Cα-Octahydro-3-Hydroxy-8β-Hydroxyacetyl-3Aα,8-Dimethyl-4H-3,10Bβ-Ethano-1H,3H-Benzo[H]Furo[4,3,2-De]-2-Benzopyran-4-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for advanced synthetic intermediates. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) and spectroscopic identification (NMR, IR) are provided to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.