Description

((E)-3-Iodo-1-Methylpropenyl)-Trimethylsilane is a high-value organosilicon reagent featuring a vinyl iodide moiety protected by a trimethylsilyl group. This compound matters as a versatile and stable synthetic building block, enabling precise carbon-carbon bond formation in complex molecule assembly. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing key intermediates.

Application

• Pharmaceutical Intermediate Synthesis: A key precursor in cross-coupling reactions (e.g., Stille, Suzuki-Miyaura) for constructing complex drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of novel pesticides and herbicides, where the vinyl iodide functionality allows for the introduction of specific aromatic or heterocyclic systems.
• Material Science & Liquid Crystal Development: Serves as a building block for creating functionalized organic molecules used in advanced materials and liquid crystal displays (LCDs).
• Organic Synthesis & Methodology Development: Employed in academic and industrial labs for developing new catalytic cycles and synthetic methodologies involving vinyl metal species.
• Fine Chemical Production: Utilized in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring stereoselective transformations.

Basic Information

Product Name	((E)-3-Iodo-1-Methylpropenyl)-Trimethylsilane
CAS No.	52685-51-5
Molecular Formula	C7H15ISi
Molecular Weight	254.18 g/mol
Synonyms	(E)-1-Iodo-3-(trimethylsilyl)-2-butene; (E)-3-Iodo-1-methyl-1-(trimethylsilyl)propene; 1-Methyl-1-(trimethylsilyl)-3-iodopropene (E)-; Trimethyl[(1E)-3-iodo-1-methyl-1-propen-1-yl]silane; (E)-3-Iodo-1-methylpropenyltrimethylsilane; (E)-1-Methyl-1-trimethylsilyl-3-iodopropene; (E)-β-Iodovinylsilane derivative
EINECS	Contact for details

Quality Control

Our ((E)-3-Iodo-1-Methylpropenyl)-Trimethylsilane is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR (1H, 13C), GC/HPLC, and Karl Fischer titration, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Isomeric Purity (E/Z ratio)	≥ 95:5 (E:Z)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.