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Polyoxy(Methyl-1,2-Ethanediyl), .Alpha.-Hydro-.Omega.-Hydroxy-, Ether With D-Glucitol (6:1) CAS NO 52625-13-5


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CAS No.:52625-13-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Polyoxy(Methyl-1,2-Ethanediyl), .Alpha.-Hydro-.Omega.-Hydroxy-, Ether With D-Glucitol (6:1) is a non-ionic surfactant and emulsifier belonging to the class of sorbitan ethoxylates, specifically a polyoxyethylene sorbitan derivative. This compound is valued for its excellent solubilizing, wetting, and stabilizing properties in complex formulations. It is a critical ingredient for manufacturers in the pharmaceutical, cosmetic, and food industries, where consistent performance and regulatory compliance are paramount. Its versatility makes it essential for creating stable emulsions and enhancing the bioavailability of active ingredients.

Application

  • Pharmaceutical Formulations: Used as a solubilizer and emulsifier in oral, topical, and injectable drug products to improve the dissolution of poorly water-soluble active pharmaceutical ingredients (APIs).
  • Cosmetics & Personal Care: Acts as a key surfactant and emulsifying agent in creams, lotions, shampoos, and makeup, providing stability and a smooth texture.
  • Food Industry (as permitted): Employed as an emulsifier and dispersant in food products, baked goods, and edible coatings to ensure uniform texture and prevent separation.
  • Industrial Applications: Serves as a wetting agent, dispersant, and stabilizer in agrochemicals, paints, coatings, and textile processing chemicals.
  • Laboratory & Biotechnology: Utilized in cell culture media and biochemical research as a non-ionic detergent for membrane protein solubilization.

Basic Information

Product Name Polyoxy(Methyl-1,2-Ethanediyl), .Alpha.-Hydro-.Omega.-Hydroxy-, Ether With D-Glucitol (6:1)
CAS No. 52625-13-5
Molecular Formula C32H62O13 (Representative for core structure; exact formula may vary with ethoxylation degree)
Molecular Weight ~654.8 g/mol (Average)
Synonyms Polysorbate 20; Tween 20; Polyoxyethylene (20) sorbitan monolaurate; Sorbitan, monolaurate, poly(oxy-1,2-ethanediyl) derivs.; Ethoxylated sorbitan monolaurate; POE (20) sorbitan monolaurate; (Oxy-1,2-ethanediyl).alpha.-hydro-.omega.-hydroxy-, ether with D-glucitol, monolaurate; PEG-20 sorbitan laurate
EINECS 258-068-5

Quality Control

Our Polyoxy(Methyl-1,2-Ethanediyl), .Alpha.-Hydro-.Omega.-Hydroxy-, Ether With D-Glucitol (6:1) is manufactured under strict quality management systems. We offer grades compliant with USP-NF, Ph. Eur., and FCC monographs where applicable, ensuring suitability for pharmaceutical, cosmetic, and food applications. Every batch undergoes rigorous analytical testing, including assay, impurity profiling, and physical characterization. Certificates of Analysis (COA) documenting full compliance with specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use to prevent absorption of atmospheric moisture.

Specification

Item Specification
Appearance Clear, viscous yellow to amber liquid
Identification (IR) Conforms
Assay (Saponification Value) 40 - 50 mg KOH/g
Hydroxyl Value 96 - 108 mg KOH/g
Acid Value ≤ 2.0 mg KOH/g
Water Content (KF) ≤ 3.0 % w/w
Residue on Ignition ≤ 0.25 % w/w
Heavy Metals (as Pb) ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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