Description

3,3-Dimethylbicyclo[2.2.1]heptane-2-carboxylic acid is a specialized, high-purity carboxylic acid derivative featuring a rigid bicyclic framework. This unique structure makes it a valuable and versatile chiral building block and intermediate in advanced organic synthesis. It is primarily sought after by R&D and production teams in the pharmaceutical and fine chemical industries for developing novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new therapeutic agents, particularly for creating molecules with specific three-dimensional shapes.
• Asymmetric Synthesis: Utilized as a precursor or auxiliary in catalytic asymmetric reactions to induce chirality in target molecules.
• Ligand and Catalyst Development: The carboxylic acid group and rigid backbone are useful for constructing novel ligands for metal catalysis or organocatalysts.
• Fine Chemical Production: Acts as a building block for synthesizing specialty chemicals, flavors, fragrances, and advanced materials.
• Academic and Industrial Research: Employed in methodological studies and process chemistry for exploring new synthetic routes.
• Agrochemical Intermediates: Potential use in the synthesis of advanced, structurally complex active ingredients for crop protection.

Basic Information

Item	Details
Product Name	3,3-Dimethylbicyclo[2.2.1]heptane-2-carboxylic Acid
CAS No.	52557-98-9
Molecular Formula	C10H16O2
Molecular Weight	168.23 g/mol
Synonyms	2-Norbornanecarboxylic acid, 3,3-dimethyl-; 3,3-Dimethyl-2-norbornanecarboxylic acid; 3,3-Dimethylbicyclo[2.2.1]heptane-2-carboxylic acid; 3,3-Dimethylnorbornane-2-carboxylic acid; exo-3,3-Dimethylbicyclo[2.2.1]heptane-2-carboxylic acid; endo-3,3-Dimethylbicyclo[2.2.1]heptane-2-carboxylic acid (stereoisomers); 3,3-Dimethyl-2-bornanecarboxylic acid
EINECS	Contact for details

Quality Control

Our 3,3-Dimethylbicyclo[2.2.1]heptane-2-carboxylic acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring it meets the exacting standards required for advanced synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (for specified isomer)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.