Description

(14R,16R)-1α-Acetoxy-7α,20-Epoxy-6β,7,14-Trihydroxy-17-Methoxykaurane-15-One is a high-purity, structurally complex diterpenoid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound matters as a sophisticated chemical intermediate, offering a unique kaurane skeleton functionalized with multiple oxygenated groups, which is valuable for constructing novel molecular architectures. It is primarily needed by research institutions and pharmaceutical development laboratories focused on medicinal chemistry, natural product synthesis, and the exploration of new bioactive compounds.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel drug candidates, particularly those targeting complex biological pathways.
• Medicinal Chemistry Research: Used as a reference standard or a starting material for structure-activity relationship (SAR) studies in drug discovery programs.
• Natural Product Synthesis: Acts as a critical intermediate in the total or semi-synthesis of complex diterpenoid natural products and their analogs.
• Biochemical Research: Employed in studies investigating enzyme interactions or as a probe for specific biological targets due to its intricate stereochemistry.
• Advanced Organic Synthesis: Utilized in methodological development for challenging chemical transformations, such as selective functionalization of polyoxygenated systems.

Basic Information

Product Name	(14R,16R)-1α-Acetoxy-7α,20-Epoxy-6β,7,14-Trihydroxy-17-Methoxykaurane-15-One
CAS No.	52554-74-2
Molecular Formula	C23H32O9
Molecular Weight	452.50 g/mol
Synonyms	1α-Acetoxy-7α,20-epoxy-6β,7,14-trihydroxy-17-methoxykauran-15-one; (14R,16R)-1α-Acetoxy-7α,20-epoxy-6β,7,14-trihydroxy-17-methoxykauran-15-one; Kaurane diterpenoid derivative; 7α,20-Epoxy-1α-acetoxy-6β,7,14-trihydroxy-17-methoxykauran-15-one; 52554-74-2; Ent-1α-acetoxy-7α,20-epoxy-6β,7,14-trihydroxy-17-methoxykauran-15-one
EINECS	Contact for details

Quality Control

Our (14R,16R)-1α-Acetoxy-7α,20-Epoxy-6β,7,14-Trihydroxy-17-Methoxykaurane-15-One is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to rigorous analytical standards utilizing techniques such as HPLC, NMR, and MS to verify chemical identity and purity, ensuring the material meets the exacting requirements of pharmaceutical and synthetic chemistry research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation. Keep the container tightly sealed when not in use to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.