Description

(5R)-6α-[2-(1,3-Benzodioxol-5-Yl)Ethyl]-5,6-Dihydro-4,5α-Dimethoxy-2H-Pyran-2-One is a high-purity, complex organic compound with a unique pyranone core structure, serving as a critical intermediate for advanced chemical synthesis. Its value lies in providing a versatile chiral building block for pharmaceutical research and the development of novel active ingredients. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to create new molecules with specific biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) targets.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its complex heterocyclic structure for bioactivity.
• Fine Chemical Production: Serves as a specialized building block for synthesizing complex natural product analogs and other high-value specialty chemicals.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in asymmetric synthesis and heterocyclic chemistry.
• Process Chemistry: Used for scaling up synthetic routes and optimizing manufacturing processes for target molecules in pilot plants.

Basic Information

Product Name	(5R)-6α-[2-(1,3-Benzodioxol-5-Yl)Ethyl]-5,6-Dihydro-4,5α-Dimethoxy-2H-Pyran-2-One
CAS No.	52526-01-9
Molecular Formula	C₁₈H₂₂O₆
Molecular Weight	334.37 g/mol
Synonyms	6α-[2-(1,3-Benzodioxol-5-yl)ethyl]-5,6-dihydro-4,5α-dimethoxy-2H-pyran-2-one; (5R)-6α-(2-(1,3-Benzodioxol-5-yl)ethyl)-5,6-dihydro-4,5α-dimethoxy-2H-pyran-2-one; 5,6-Dihydro-4,5-dimethoxy-6-[2-(3,4-methylenedioxyphenyl)ethyl]-2H-pyran-2-one; CAS 52526-01-9; 2H-Pyran-2-one, 6-[2-(1,3-benzodioxol-5-yl)ethyl]-5,6-dihydro-4,5-dimethoxy-, (5R,6α)-; (5R,6α)-6-[2-(1,3-Benzodioxol-5-yl)ethyl]-5,6-dihydro-4,5-dimethoxy-2H-pyran-2-one
EINECS	Contact for details

Quality Control

Our (5R)-6α-[2-(1,3-Benzodioxol-5-Yl)Ethyl]-5,6-Dihydro-4,5α-Dimethoxy-2H-Pyran-2-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.