Description

(5S)-6α-[(E)-2-(1,3-Benzodioxol-5-Yl)Ethenyl]-5,6-Dihydro-5β-Hydroxy-4-Methoxy-2H-Pyran-2-One CAS NO 52525-98-1 is a high-purity, complex organic compound belonging to the class of substituted pyran-2-ones. This compound is valued for its specific stereochemistry and functional groups, making it a critical advanced intermediate or reference standard in sophisticated chemical synthesis. It is primarily required by research institutions and pharmaceutical development companies engaged in the discovery and production of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of complex drug molecules, particularly in research for new therapeutic agents.
• Chemical Reference Standard: Used for analytical method development, validation, and quality control (QC) in laboratories to ensure product identity and purity.
• Organic Synthesis Research: Acts as a precursor or model compound in academic and industrial research exploring new synthetic methodologies, especially those involving lactones and benzodioxole derivatives.
• Biochemical Research: Potential use in studying biological activity and structure-activity relationships (SAR) due to its specific molecular architecture.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals where high stereochemical purity is essential.

Basic Information

Product Name	(5S)-6α-[(E)-2-(1,3-Benzodioxol-5-Yl)Ethenyl]-5,6-Dihydro-5β-Hydroxy-4-Methoxy-2H-Pyran-2-One
CAS No.	52525-98-1
Molecular Formula	C₁₇H₁₆O₆
Molecular Weight	316.31 g/mol
Synonyms	6-[(E)-2-(1,3-Benzodioxol-5-yl)ethenyl]-5,6-dihydro-5-hydroxy-4-methoxy-2H-pyran-2-one; (5S,6R)-6-[(E)-2-(1,3-Benzodioxol-5-yl)vinyl]-5,6-dihydro-5-hydroxy-4-methoxy-2H-pyran-2-one; 5,6-Dihydro-5-hydroxy-4-methoxy-6-[(E)-2-(3,4-methylenedioxyphenyl)ethenyl]-2H-pyran-2-one; (5S)-6-[(E)-2-(Benzo[d][1,3]dioxol-5-yl)vinyl]-5,6-dihydro-5-hydroxy-4-methoxy-2H-pyran-2-one; A related Kava lactone derivative
EINECS	Contact for details

Quality Control

Our (5S)-6α-[(E)-2-(1,3-Benzodioxol-5-Yl)Ethenyl]-5,6-Dihydro-5β-Hydroxy-4-Methoxy-2H-Pyran-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring compliance with research and development grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.