Description

2-Chloro-3-Methoxybenzyl Chloride is a versatile and reactive benzyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized aromatic core that enables the construction of complex molecules for high-value applications. This intermediate is essential for research and production in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the manufacturing of herbicides, fungicides, and insecticides, where its chlorinated methoxybenzene structure contributes to biological activity.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Acts as a monomer or functionalization agent in the development of advanced polymers and liquid crystals.
• Dye and Pigment Intermediate: Utilized in the synthesis of complex organic dyes and pigments for industrial applications.
• Custom Synthesis and R&D: Serves as a starting material for contract research organizations and fine chemical companies engaged in custom synthesis projects.

Basic Information

Product Name	2-Chloro-3-Methoxybenzyl Chloride
CAS No.	52516-44-6
Molecular Formula	C8H8Cl2O
Molecular Weight	191.05 g/mol
Synonyms	1-(Chloromethyl)-2-chloro-3-methoxybenzene; 2-Chloro-3-methoxybenzyl chloride; 3-Methoxy-2-chlorobenzyl chloride; (2-Chloro-3-methoxyphenyl)methyl chloride; α,2-Dichloro-3-methoxytoluene; 2-Chloro-3-methoxy-α-chlorotoluene; Benzene, 1-(chloromethyl)-2-chloro-3-methoxy-
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Methoxybenzyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Density	~1.30 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.