Description

Cyclohexanecarboxylic Acid, 1-Amino-3-(Methylthio)- (9Ci) is a specialized chiral intermediate featuring both amino and methylthio functional groups on a cyclohexane carboxylic acid backbone. This unique structure makes it a valuable building block for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by research institutions and manufacturers developing active pharmaceutical ingredients (APIs), advanced crop protection agents, and novel fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its functional groups for bioactivity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis and metal complex formation.
• Peptidomimetics Research: The amino acid-like structure is valuable for creating constrained peptide analogs in medicinal chemistry.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals for material science and electronics applications.
• Academic & R&D: Utilized in university and corporate research laboratories for exploring new synthetic methodologies and compound libraries.

Basic Information

Product Name	Cyclohexanecarboxylic Acid, 1-Amino-3-(Methylthio)- (9Ci)
CAS No.	52474-43-8
Molecular Formula	C9H17NO2S
Molecular Weight	203.30 g/mol
Synonyms	1-Amino-3-(methylthio)cyclohexanecarboxylic acid; (1R,3S)-1-Amino-3-(methylsulfanyl)cyclohexane-1-carboxylic acid; trans-1-Amino-3-(methylthio)cyclohexanecarboxylic acid; 3-(Methylthio)-1-aminocyclohexanecarboxylic acid; Cyclohexanecarboxylic acid, 1-amino-3-(methylthio)-, trans-; AMTCHA; A building block for chiral synthesis.
EINECS	Contact for details

Quality Control

Our Cyclohexanecarboxylic Acid, 1-Amino-3-(Methylthio)- (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support custom synthesis and can tailor specifications to meet specific research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (typical)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.