Description

2-Bromo-4-Nitrophenol is a halogenated nitrophenol derivative that serves as a versatile and critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both bromine and nitro substituents, makes it a valuable building block for constructing complex molecules with specific electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop active ingredients, dyes, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic scaffolds.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and pesticides, where the bromo and nitro groups contribute to biological activity.
• Dye and Pigment Manufacturing: Serves as an intermediate for azo dyes and other complex colorants, providing chromophore and auxochrome elements.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce functionalized phenol groups.
• Research & Development: Utilized in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Material Science: Potential intermediate in the synthesis of monomers for polymers or ligands for metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Bromo-4-Nitrophenol
CAS No.	52427-05-1
Molecular Formula	C6H4BrNO3
Molecular Weight	218.01 g/mol
Synonyms	2-Bromo-4-nitrophenol; 4-Nitro-2-bromophenol; Phenol, 2-bromo-4-nitro-; 2-Brom-4-nitrophenol; NSC 403697; 2-Bromo-4-hydroxy-nitrobenzene; o-Bromo-p-nitrophenol
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Nitrophenol is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber or otherwise opaque, or stored in dark conditions.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	118°C - 122°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.