Description

Duartin (-) CAS NO 52305-04-1 is a high-purity, enantiomerically pure flavanone derivative, a key chiral building block and reference standard in advanced chemical synthesis. Its defined stereochemistry and consistent quality are critical for research and development in pharmaceuticals and fine chemicals, where precise molecular structure directly impacts biological activity and process outcomes. This compound is essential for scientists and manufacturers in the pharmaceutical, agrochemical, and nutraceutical industries who require reliable, high-grade chiral intermediates for API development and analytical applications.

Application

• Pharmaceutical Intermediate: Serves as a chiral precursor in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Analytical Reference Standard: Used for method development, calibration, and quality control in HPLC, LC-MS, and chiral separation techniques.
• Biochemical Research: Employed in studies of flavonoid metabolism, enzyme inhibition assays, and structure-activity relationship (SAR) investigations.
• Fine Chemical Synthesis: A valuable building block for creating complex, optically active molecules in agrochemical and specialty chemical production.
• Nutraceutical & Cosmetic Ingredient Development: Used in R&D for high-value bioactive compounds with antioxidant or other targeted properties.

Basic Information

Product Name	Duartin (-)
CAS No.	52305-04-1
Molecular Formula	C17H16O6
Molecular Weight	316.31 g/mol
Synonyms	(-)-Duartin; (2S)-7-Hydroxy-3-(4-hydroxy-2-methoxyphenyl)-2,3-dihydro-4H-chromen-4-one; (S)-Duartin; 2,3-Dihydro-7-hydroxy-3-(4-hydroxy-2-methoxyphenyl)-4H-1-benzopyran-4-one, (S)-; Duartin enantiomer; NSC 407303; Flavonoid Duartin
EINECS	Contact for details

Quality Control

Our Duartin (-) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as chiral purity, chemical identity, and impurity profiles. We support compliance with cGMP, ICH guidelines, and relevant pharmacopeial standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.