Description

(5R,6S)-5,6-Dihydro-5-Hydroxy-4-Methoxy-6-[(E)-2-Phenylethenyl]-2H-Pyran-2-One is a high-purity, optically active lactone derivative with a complex stereochemistry. This compound serves as a valuable chiral building block and intermediate in advanced organic synthesis, particularly for the development of pharmaceuticals and bioactive molecules. It is primarily sought by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and fine chemical sectors for its specific structural and stereochemical features.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting specific biological pathways.
• Organic Synthesis Building Block: Used in asymmetric synthesis to construct complex molecular architectures, leveraging its defined (5R,6S) stereochemistry.
• Medicinal Chemistry Research: Employed in drug discovery programs for structure-activity relationship (SAR) studies and lead optimization.
• Agrochemical Development: Potential intermediate in the research and synthesis of novel, high-efficacy crop protection agents.
• Academic & Industrial R&D: Serves as a reference standard and starting material for methodological development in synthetic organic chemistry.

Basic Information

Product Name	(5R,6S)-5,6-Dihydro-5-Hydroxy-4-Methoxy-6-[(E)-2-Phenylethenyl]-2H-Pyran-2-One
CAS No.	52247-79-7
Molecular Formula	C15H16O4
Molecular Weight	260.29 g/mol
Synonyms	(5R,6S)-5,6-Dihydro-5-hydroxy-4-methoxy-6-[(E)-2-phenylethenyl]-2H-pyran-2-one; (5R,6S)-5,6-Dihydro-5-hydroxy-4-methoxy-6-styryl-2H-pyran-2-one; 5,6-Dihydro-5-hydroxy-4-methoxy-6-[(E)-2-phenylethenyl]-2H-pyran-2-one; 5,6-Dihydro-5-hydroxy-4-methoxy-6-styryl-2H-pyran-2-one; (E)-5,6-Dihydro-5-hydroxy-4-methoxy-6-styryl-2H-pyran-2-one; 5-Hydroxy-4-methoxy-6-styryl-5,6-dihydro-2H-pyran-2-one; CAS 52247-79-7
EINECS	Contact for details

Quality Control

Our (5R,6S)-5,6-Dihydro-5-Hydroxy-4-Methoxy-6-[(E)-2-Phenylethenyl]-2H-Pyran-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure high chemical and stereochemical purity suitable for research and development applications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.