Description

1-Chloro-2-(Trifluoromethyl)Benzene is a versatile halogenated aromatic building block of significant industrial importance. Its unique structure, featuring both chlorine and trifluoromethyl substituents, makes it a critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients. This compound is essential for manufacturers in the agrochemical, pharmaceutical, and specialty chemical sectors seeking to introduce specific functional groups and enhance molecular properties.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of modern herbicides, fungicides, and insecticides, where the trifluoromethyl group improves biological activity and environmental stability.
• Pharmaceutical Synthesis: Serves as a vital building block for creating active pharmaceutical ingredients (APIs), particularly in the development of compounds with enhanced metabolic stability and bioavailability.
• Liquid Crystal & OLED Materials: Used in the production of advanced electronic display components, where its aromatic and halogenated structure contributes to desired electronic and physical properties.
• Polymer & Resin Modification: Acts as a monomer or modifier in the synthesis of specialty polymers, imparting specific characteristics like chemical resistance or altered solubility.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Negishi) and as a starting material for further functionalization to create complex organic molecules.
• Dye & Pigment Manufacturing: Utilized in the synthesis of specialized dyes and pigments, where the chlorine and trifluoromethyl groups influence color fastness and solubility.

Basic Information

Product Name	1-Chloro-2-(Trifluoromethyl)Benzene
CAS No.	52181-51-8
Molecular Formula	C7H4ClF3
Molecular Weight	180.55 g/mol
Synonyms	2-Chloro-α,α,α-trifluorotoluene; 2-Chlorobenzotrifluoride; o-Chlorobenzotrifluoride; 2-Chloro-α,α,α-trifluoromethylbenzene; 1-Chloro-2-(trifluoromethyl)benzene; 2-Chlorotrifluoromethylbenzene; o-Chloro-α,α,α-trifluorotoluene; Benzene, 1-chloro-2-(trifluoromethyl)-
EINECS	257-664-5

Quality Control

Our 1-Chloro-2-(Trifluoromethyl)Benzene is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee compliance with your specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	Individual impurity ≤ 0.5%
Density (20°C)	1.35 - 1.38 g/mL
Refractive Index (20°C)	1.445 - 1.455

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.