Description

(E)-4-[(S)-2,2-Dimethylcyclobutyl]-3-Buten-2-One is a high-purity chiral building block featuring a defined stereochemistry and an α,β-unsaturated ketone moiety. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and fine chemical sectors. It is primarily sought after by research and development teams and process chemists for constructing novel active pharmaceutical ingredients (APIs), flavors, and fragrances. The defined (E)-alkene and (S)-stereocenter provide precise structural control for advanced synthetic applications.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel therapeutic agents and active pharmaceutical ingredients (APIs).
• Fine Chemical Synthesis: Used in the multi-step synthesis of complex organic molecules for research and specialty chemical production.
• Flavor & Fragrance Industry: Serves as a precursor for the creation of specific aroma compounds and flavoring agents.
• Agrochemical Research: Potential building block in the development of new crop protection agents and pesticides.
• Material Science: Can be utilized in the synthesis of specialized monomers or ligands for advanced materials.
• Academic & Industrial R&D: Employed in methodological studies and as a standard in asymmetric synthesis and catalysis research.

Basic Information

Product Name	(E)-4-[(S)-2,2-Dimethylcyclobutyl]-3-Buten-2-One
CAS No.	51847-79-1
Molecular Formula	C10H16O
Molecular Weight	152.23 g/mol
Synonyms	(S,E)-4-(2,2-Dimethylcyclobutyl)but-3-en-2-one; (E)-4-[(2S)-2,2-Dimethylcyclobutyl]-3-buten-2-one; 3-Buten-2-one, 4-[(1S)-2,2-dimethylcyclobutyl]-, (3E)-; (E)-4-[(S)-2,2-Dimethylcyclobutyl]but-3-en-2-one; 51847-79-1; (S,E)-4-(2,2-Dimethylcyclobutyl)-3-buten-2-one
EINECS	Contact for details

Quality Control

Our (E)-4-[(S)-2,2-Dimethylcyclobutyl]-3-Buten-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC and structural confirmation by NMR and IR spectroscopy, to ensure high chemical and isomeric purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.