Description

2-Acetylamino-2-Deoxy-4-O,6-o-Isopropylidene-D-Gluconic Acid δ-Lactone is a high-purity, advanced chiral intermediate and building block in organic synthesis. Its locked isopropylidene-protected structure makes it a valuable precursor for the synthesis of complex carbohydrates, nucleoside analogs, and other biologically active molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries developing novel therapeutics and diagnostic agents.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of nucleoside-based antiviral and anticancer drugs.
• Carbohydrate Chemistry: Serves as a protected glycosyl donor or acceptor in the synthesis of complex oligosaccharides and glycoconjugates.
• Bioconjugation: Used in the development of antibody-drug conjugates (ADCs) and other targeted delivery systems.
• Glycomimetics Research: Fundamental starting material for creating sugar analogs that inhibit enzymes or modulate biological pathways.
• Fine Chemical Synthesis: Intermediate in the production of specialty chemicals, catalysts, and ligands for asymmetric synthesis.
• Diagnostic Reagent Development: Used in the manufacture of labeled probes and assay components for biomedical research.

Basic Information

Product Name	2-Acetylamino-2-Deoxy-4-O,6-o-Isopropylidene-D-Gluconic Acid δ-Lactone
CAS No.	51844-23-6
Molecular Formula	C11H15NO6
Molecular Weight	257.24 g/mol
Synonyms	1,2-O-Isopropylidene-5-acetamido-5-deoxy-D-glucofuranurono-6,3-lactone; 5-Acetamido-5-deoxy-1,2-O-isopropylidene-α-D-glucofuranurono-6,3-lactone; 2-Acetamido-2-deoxy-4,6-O-isopropylidene-D-gluconic acid δ-lactone; Isopropylidene-N-acetyl-D-glucosaminuronic acid lactone; D-Glucofuranurono-6,3-lactone, 5-acetamido-5-deoxy-1,2-O-isopropylidene-
EINECS	Contact for details

Quality Control

Every batch of 2-Acetylamino-2-Deoxy-4-O,6-o-Isopropylidene-D-Gluconic Acid δ-Lactone is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure the identity, purity, and consistency required for sensitive R&D and cGMP manufacturing. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.