Description

6-Phenyl-Pyridazine-3-Thiol is a versatile heterocyclic building block featuring a pyridazine core substituted with a phenyl group and a thiol moiety. This compound is valued for its role as a key intermediate in the synthesis of more complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working on active ingredients, ligands, and functional materials. The specific molecular architecture offers unique reactivity for constructing nitrogen- and sulfur-containing scaffolds.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Research: Used in developing new active ingredients for herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Investigated for incorporation into organic electronic materials, dyes, and pigments due to its conjugated system.
• Chemical Biology Probes: Utilized in the design of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	6-Phenyl-Pyridazine-3-Thiol
CAS No.	51841-95-3
Molecular Formula	C10H8N2S
Molecular Weight	188.25 g/mol
Synonyms	3-Mercapto-6-phenylpyridazine; 6-Phenyl-3-pyridazinethiol; 6-Phenyl-3-mercaptopyridazine; 3-Pyridazinethiol, 6-phenyl-; 6-Phenylpyridazine-3-thione (tautomer); 3-Thiol-6-phenylpyridazine; 6-Phenyl-3(2H)-pyridazinethione
EINECS	Contact for details

Quality Control

Our 6-Phenyl-Pyridazine-3-Thiol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, related substances, and residual solvents. Our quality commitment supports applications in regulated environments, including pharmaceutical R&D and cGMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening the primary container. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.