Description

2(3H)-Furanone,3-Aminodihydro-,(3R)-(9Ci) is a chiral, non-proteinogenic amino acid derivative belonging to the class of γ-lactams, specifically a 3-aminodihydrofuran-2(3H)-one. This compound matters as a versatile and valuable chiral building block for the synthesis of complex pharmaceutical intermediates and fine chemicals. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in asymmetric synthesis and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of protease inhibitors, antiviral agents, and other bioactive molecules.
• Asymmetric Synthesis: Used as a chiral auxiliary or precursor in stereoselective chemical reactions to introduce the (3R)-aminodihydrofuranone moiety.
• Agrochemical Research: Serves as a building block for developing novel herbicides, fungicides, or plant growth regulators with specific stereochemistry.
• Peptidomimetics: Incorporated into peptide analogs to enhance stability, bioavailability, or biological activity.
• Fine Chemical Synthesis: Employed in the custom synthesis of complex, high-value specialty chemicals for research and small-scale production.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	2(3H)-Furanone,3-Aminodihydro-,(3R)-(9Ci)
CAS No.	51744-82-2
Molecular Formula	C₄H₇NO₂
Molecular Weight	101.10 g/mol
Synonyms	(R)-3-Aminodihydrofuran-2(3H)-one; (3R)-3-Aminotetrahydrofuran-2-one; (R)-3-Amino-γ-butyrolactone; 3-Amino-2(3H)-furanone, (R)-; 3-Aminodihydro-2(3H)-furanone, (3R)-; Tetrahydro-3-amino-2-furanone, (R)-; 3-Aminotetrahydro-2-furanone, (R)-; (R)-3-Aminodihydro-2(3H)-furanone
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with typical purity levels suitable for research and development applications, supported by comprehensive analytical data. Certificates of Analysis (COA) detailing identity, purity (by HPLC), chiral purity, and impurity profiles are available upon request. Specifications can be tailored to meet specific project requirements, including higher purity grades for advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation by atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.