Description

(6R,25R)-5-o-Demethyl-28-Deoxy-6,28-Epoxy-25-Ethyl-26-[(1H-Pyrrol-2-Ylcarbonyl)Oxy]Milbemycin B is a semi-synthetic derivative of the milbemycin family, a class of macrolide compounds known for their potent biological activity. This specific analog is engineered for enhanced stability and targeted efficacy, making it a valuable intermediate in advanced research and development. It is primarily utilized by the agrochemical and pharmaceutical industries for the development of next-generation acaricides, insecticides, and potential therapeutic agents.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of novel, high-performance veterinary and crop protection agents targeting mites and insects.
• Pharmaceutical Research: Serves as a critical building block for the development of new antiparasitic and antimicrobial drug candidates.
• Biochemical Studies: Used as a reference standard or probe in mode-of-action studies to understand interactions with invertebrate nervous systems.
• Veterinary Product Development: Employed in R&D for creating new formulations for animal health, particularly against ectoparasites.

Basic Information

Product Name	(6R,25R)-5-o-Demethyl-28-Deoxy-6,28-Epoxy-25-Ethyl-26-[(1H-Pyrrol-2-Ylcarbonyl)Oxy]Milbemycin B
CAS No.	51596-15-7
Molecular Formula	C₃₄H₄₇NO₈
Molecular Weight	597.75 g/mol
Synonyms	5-O-Demethyl-28-deoxy-6,28-epoxy-25-ethyl-26-[(1H-pyrrol-2-ylcarbonyl)oxy]milbemycin B; Milbemycin B derivative; 26-Pyrrole-2-carboxylmilbemycin B analog; LL-F28249 derivative; Nemadectin analog; 51596-15-7; (6R,25R)-form
EINECS	Contact for details

Quality Control

Our (6R,25R)-5-o-Demethyl-28-Deoxy-6,28-Epoxy-25-Ethyl-26-[(1H-Pyrrol-2-Ylcarbonyl)Oxy]Milbemycin B is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for research and development use. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.