Description

(6R,25R)-28-Deoxy-6,28-Epoxy-25-Methylmilbemycin B is a high-purity, semi-synthetic derivative of the milbemycin family of 16-membered macrolides, valued for its potent biological activity. This compound serves as a critical advanced intermediate in the synthesis of novel acaricides and anthelmintic agents for veterinary and agricultural applications. It is essential for research institutions and fine chemical manufacturers focused on developing next-generation parasitic control solutions.

Application

• Key Intermediate for Acaricide Synthesis: A vital building block in the production of modern miticides and tick control agents.
• Veterinary Pharmaceutical Research: Used in the R&D of novel anthelmintic drugs for livestock and companion animals.
• Agrochemical Development: Employed in creating new formulations for crop protection against mites and nematodes.
• Biochemical Studies: Serves as a reference standard and tool compound for investigating macrocyclic lactone mechanisms of action.
• Fine Chemical Manufacturing: Supplied to contract manufacturing organizations (CMOs) for custom synthesis projects.

Basic Information

Product Name	(6R,25R)-28-Deoxy-6,28-Epoxy-25-Methylmilbemycin B
CAS No.	51596-12-4
Molecular Formula	C₃₂H₄₆O₇
Molecular Weight	542.71 g/mol
Synonyms	28-Deoxy-6,28-epoxy-25-methylmilbemycin B; 25-Methylmilbemycin β; LL-F28249-α; Nemadectin intermediate; Milbemycin B derivative; (6R,25R)-28-Deoxy-6,28-epoxy-25-methylmilbemycin β; 51596-12-4
EINECS	Contact for details

Quality Control

Our (6R,25R)-28-Deoxy-6,28-Epoxy-25-Methylmilbemycin B is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for advanced pharmaceutical intermediates. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.