Description

n-[(R)-3-Oxoisoxazolidin-4-Yl]Acetamide is a high-purity chiral building block and synthetic intermediate of significant interest in advanced organic synthesis. Its value lies in its well-defined stereochemistry and functionalized isoxazolidine core, which serves as a versatile scaffold for constructing complex, biologically active molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of potential drug candidates, particularly those targeting infectious diseases or central nervous system disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides with specific stereochemical requirements for enhanced activity.
• Asymmetric Synthesis: Employed as a building block in catalytic asymmetric reactions to introduce chirality into target molecules.
• Peptidomimetics & Bioisosteres: The isoxazolidine ring can act as a surrogate for peptide bonds or other heterocycles in designing enzyme inhibitors.
• Academic & R&D Laboratories: Serves as a standard or starting material for methodological studies in organic and medicinal chemistry.
• Fine Chemical Production: Utilized in the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	n-[(R)-3-Oxoisoxazolidin-4-Yl]Acetamide
CAS No.	51541-30-1
Molecular Formula	C5H8N2O3
Molecular Weight	144.13 g/mol
Synonyms	(R)-4-Acetamido-3-isoxazolidinone; (4R)-4-Acetamido-1,2-oxazolidin-3-one; Acetamide, N-[(4R)-3-oxo-1,2-oxazolidin-4-yl]-; (R)-N-(3-Oxoisoxazolidin-4-yl)acetamide; 4-Acetamido-3-isoxazolidinone, (R)-; (R)-4-(Acetylamino)-3-isoxazolidinone; Chiral Isoxazolidinone Acetamide; 51541-30-1
EINECS	Contact for details

Quality Control

Our n-[(R)-3-Oxoisoxazolidin-4-Yl]Acetamide is produced under strict quality management protocols to ensure batch-to-batch consistency and high chiral purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, NMR for structural confirmation, and standard purity assays. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.