Description

2-Acetamido-2-Deoxy-1-Thio-β-D-Glucopyranose 3,4,6-Triacetate is a key thioglycoside derivative and protected intermediate in synthetic carbohydrate chemistry. This compound is valued for its role as a versatile building block in the synthesis of complex oligosaccharides, glycoconjugates, and glycomimetics. It is primarily required by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, diagnostic tools, and biochemical probes.

Application

• Glycosylation Reagent: Acts as a crucial thioglycosyl donor for the stereoselective construction of glycosidic bonds in oligosaccharide synthesis.
• Pharmaceutical Intermediate: Serves as a protected precursor in the synthesis of glycosidase inhibitors, antiviral agents, and other bioactive carbohydrate-based drugs.
• Glycoconjugate Synthesis: Used in the preparation of glycopeptides, glycolipids, and other complex biomolecules for biological studies and vaccine development.
• Chemical Biology Research: Employed as a tool compound for studying carbohydrate-protein interactions, enzyme mechanisms, and cell surface recognition processes.
• Standards and Reference Material: Provides a high-purity standard for analytical method development and quality control in carbohydrate chemistry.

Basic Information

Product Name	2-Acetamido-2-Deoxy-1-Thio-β-D-Glucopyranose 3,4,6-Triacetate
CAS No.	51450-09-0
Molecular Formula	C₁₆H₂₃NO₉S
Molecular Weight	405.42 g/mol
Synonyms	1-Thio-2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranose; 2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-1-thio-β-D-glucopyranose; 2-Acetamido-2-deoxy-1-thio-β-D-glucopyranose triacetate; 1-Thio-N-acetyl-β-D-glucosamine triacetate; Ac₃GlcNAcβ-SH; Thioglycoside of N-acetylglucosamine triacetate; β-D-GlcNAc(1S) triacetate; N-Acetyl-1-thio-β-D-glucosamine triacetate
EINECS	Contact for details

Quality Control

Our 2-Acetamido-2-Deoxy-1-Thio-β-D-Glucopyranose 3,4,6-Triacetate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and chiral analysis to ensure stereochemical integrity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specified parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	-15° to -25° (c=1 in CHCl₃)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.