Description

[1S-(1Alpha,2Beta,5Alpha)]-5-(Isopropyl)-2-Methylcyclohexyl Acetate is a high-purity, stereochemically defined organic ester, a key intermediate and building block in advanced organic synthesis. Its precise stereochemistry and functional group make it a valuable asset for research and production where molecular specificity is critical. This compound is primarily sought by the pharmaceutical, agrochemical, and fine chemical industries for applications in chiral synthesis, fragrance development, and the creation of complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for the synthesis of active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where the isopropyl-methylcyclohexyl structure imparts specific biological activity.
• Fine Chemical Production: Serves as a precursor for specialty chemicals, including catalysts, ligands, and other performance chemicals.
• Fragrance and Flavor Ingredient: Acts as an intermediate in the creation of complex, musky, or woody aroma chemicals for perfumery.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D for methodological studies in stereoselective synthesis and ester chemistry.
• Material Science: Potential monomer or modifier in the synthesis of specialized polymers with unique properties.

Basic Information

Product Name	[1S-(1Alpha,2Beta,5Alpha)]-5-(Isopropyl)-2-Methylcyclohexyl Acetate
CAS No.	51446-59-4
Molecular Formula	C13H24O2
Molecular Weight	212.33 g/mol
Synonyms	(-)-Menthyl Acetate (specific stereoisomer); (1S,2R,5S)-2-Isopropyl-5-methylcyclohexyl Acetate; L-Menthyl Acetate; (1S)-1,3,3-Trimethyl-2-oxabicyclo[2.2.2]octan-6-yl Acetate (related bicyclic form); p-Menth-3-yl Acetate; 5-Isopropyl-2-methylcyclohexyl Acetate, [1S-(1α,2β,5α)]-; Acetic Acid (1S,2R,5S)-1,3,3-Trimethylbicyclo[2.2.2]octan-2-yl Ester
EINECS	Contact for details

Quality Control

We maintain rigorous quality control protocols for this chiral compound, ensuring batch-to-batch consistency in purity and stereochemical integrity. Our standard grade typically meets a purity specification of ≥97% (by GC or HPLC), with enantiomeric excess (e.e.) confirmed. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing parameters such as assay, identity, specific rotation, and impurity profile. Production can be aligned with cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Specific Rotation [α]20/D	-70° to -80° (c=1 in CHCl3)
Assay (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.