Description

Cyclohexane, 1-Bromo-2-Fluoro-, cis- is a high-purity, halogenated cyclohexane derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical building block for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. Its unique stereochemistry and reactive halogen sites make it an essential intermediate for researchers and manufacturers requiring precise structural control in active ingredient development.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially those requiring fluorinated and brominated motifs for enhanced bioactivity and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the cis-configuration and halogen atoms can influence target specificity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for creating fluorinated and brominated aromatic compounds used in electronic display technologies and organic light-emitting diodes.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi) to form complex biaryl and other carbon-carbon bonds.
• Fluorine Chemistry Research: A valuable reagent for studying stereoselective fluorination reactions and the effects of adjacent halogens on reaction pathways.
• Fine Chemical & Specialty Polymer Synthesis: Employed in the production of specialty monomers, ligands for catalysis, and other high-value fine chemicals.

Basic Information

Product Name	Cyclohexane, 1-Bromo-2-Fluoro-, cis-
CAS No.	51422-74-3
Molecular Formula	C6H10BrF
Molecular Weight	181.05 g/mol
Synonyms	cis-1-Bromo-2-fluorocyclohexane; (1R,2S)-1-Bromo-2-fluorocyclohexane; (1S,2R)-1-Bromo-2-fluorocyclohexane; 1-Bromo-2-fluorocyclohexane, cis-; Bromofluorocyclohexane; Fluorobromocyclohexane
EINECS	Contact for details

Quality Control

Every batch of cis-1-Bromo-2-fluorocyclohexane is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your critical synthesis steps. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality assurance system is designed to meet the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0% (cis-isomer)
Purity (GC Area %)	≥ 98.0%
Trans-isomer (GC)	≤ 1.5%
Water Content (KF)	≤ 0.1%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.