Description

(3S)-8α-Vinyl-3A,5Aβ,7,8,9,10,10Aα,10Cβ-Octahydro-3α-Hydroxy-3Aβ,8-Dimethyl-4H-3,10Bβ-Ethano-1H,3H-Benzo[H]Furo[4,3,2-De]-2-Benzopyran-4-One is a complex, high-purity organic compound with a defined stereochemistry, serving as a critical advanced pharmaceutical intermediate or reference standard. Its intricate fused-ring structure makes it a valuable building block for the synthesis of novel active pharmaceutical ingredients (APIs) and for research into complex molecular architectures. This compound is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates, particularly in oncology and central nervous system (CNS) research.
• Reference Standard: Used for analytical method development, validation, and quality control (QC) in pharmaceutical manufacturing to ensure batch consistency and purity.
• Medicinal Chemistry Research: Serves as a core scaffold or precursor for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of target molecules under Good Manufacturing Practice (GMP) guidelines.
• Academic Research: Used in university and institutional labs for studies in organic synthesis, natural product analog development, and chemical biology.

Basic Information

Product Name	(3S)-8α-Vinyl-3A,5Aβ,7,8,9,10,10Aα,10Cβ-Octahydro-3α-Hydroxy-3Aβ,8-Dimethyl-4H-3,10Bβ-Ethano-1H,3H-Benzo[H]Furo[4,3,2-De]-2-Benzopyran-4-One
CAS No.	51415-08-8
Molecular Formula	C22H26O4
Molecular Weight	354.44 g/mol
Synonyms	8α-Vinyl-3a,5aβ,7,8,9,10,10aα,10cβ-octahydro-3α-hydroxy-3aβ,8-dimethyl-4H-3,10bβ-ethano-1H,3H-benzo[h]furo[4,3,2-de]-2-benzopyran-4-one; (3S)-8α-Vinyl-3a,5aβ,7,8,9,10,10aα,10cβ-octahydro-3α-hydroxy-3aβ,8-dimethyl-4H-3,10bβ-ethano-1H,3H-benzo[h]furo[4,3,2-de]-2-benzopyran-4-one; 8α-Vinyl-3a,5aβ,7,8,9,10,10aα,10cβ-octahydro-3α-hydroxy-3aβ,8-dimethyl-4H-3,10bβ-ethano-1H,3H-benzo[h]furo[4,3,2-de]isochromen-4-one; Furo[4,3,2-de]isochromen derivative
EINECS	Contact for details

Quality Control

Every batch of this high-value intermediate is produced and tested under a strict quality management system. We provide comprehensive analytical data to support its use in regulated environments, with specifications tailored to meet pharmaceutical research and development requirements. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Optical Rotation	Contact for details
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.