Description

3'-(3-Oxo-11 Beta,17-Dihydroxy-4-Androstene-17 α- Yl)Propionic Acid Lactone is a high-purity steroid derivative and a key advanced pharmaceutical intermediate. This compound is critical for the synthesis of complex steroid-based active pharmaceutical ingredients (APIs) where precise stereochemistry and functional group integrity are paramount. It is primarily utilized by pharmaceutical R&D laboratories and manufacturers specializing in corticosteroid, anti-inflammatory, and hormonal therapies.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of potent corticosteroid APIs and other steroidal drugs.
• Research & Development: Used in medicinal chemistry for the discovery and development of new steroid-based therapeutic agents targeting inflammation and hormonal pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for commercial pharmaceutical production.
• Biochemical Research: Used in studies investigating steroid hormone metabolism, receptor binding, and biological activity.

Basic Information

Item	Details
Product Name	3'-(3-Oxo-11 Beta,17-Dihydroxy-4-Androstene-17 α- Yl)Propionic Acid Lactone
CAS No.	51390-69-3
Molecular Formula	C22H28O5
Molecular Weight	372.46 g/mol
Synonyms	11β,17α,21-Trihydroxypregn-4-ene-3,20-dione 17α-(1-oxopropoxy), cyclic 1,2-ethanediyl acetal; 11β,17α,21-Trihydroxypregna-4-ene-3,20-dione cyclic 17,21-acetal with propionaldehyde; 17α,21-(1'-Carboxyethylidenedioxy)-11β-hydroxy-4-pregnene-3,20-dione γ-lactone; Prednisolone 17α,21-acetal lactone; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 3'-(3-Oxo-11 Beta,17-Dihydroxy-4-Androstene-17 α- Yl)Propionic Acid Lactone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis to ensure it meets exacting standards for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.