Description

(E)-3-[(R)-4-Methyl-3-Cyclohexen-1-Yl]-2-Butenoic Acid is a high-purity, chiral unsaturated carboxylic acid featuring a cyclohexene ring, making it a valuable intermediate for advanced organic synthesis. This compound is essential for the development of complex molecules where stereochemical control and specific functional group placement are critical. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for applications in drug discovery, chiral catalyst development, and the synthesis of specialty fragrances.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for anti-inflammatory and antiviral agents.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where its specific stereochemistry contributes to biological activity.
• Fine Chemical Production: Serves as a precursor for high-value specialty chemicals, including complex fragrances, flavors, and advanced material monomers.
• Chiral Catalyst & Ligand Development: Employed in the research and manufacture of enantioselective catalysts and ligands for asymmetric synthesis.
• Academic & Industrial Research: A critical reagent for methodological studies in organic chemistry, particularly in cycloaddition and conjugate addition reactions.
• Material Science: Potential monomer for creating polymers with specific optical or mechanical properties derived from its rigid cyclohexene core.

Basic Information

Product Name	(E)-3-[(R)-4-Methyl-3-Cyclohexen-1-Yl]-2-Butenoic Acid
CAS No.	51373-21-8
Molecular Formula	C11H16O2
Molecular Weight	180.24 g/mol
Synonyms	(R,E)-3-(4-Methylcyclohex-3-en-1-yl)but-2-enoic Acid; (E)-3-[(4R)-4-Methyl-3-cyclohexen-1-yl]-2-butenoic Acid; 4-Methyl-δ³-cyclohexene-1-butenoic Acid; (R)-4-Methyl-3-cyclohexene-1-ylidenepropionic Acid; (E)-3-(p-Menth-1-en-6-yl)acrylic Acid (related terpenoid name); (2E)-3-[(4R)-4-Methyl-3-cyclohexen-1-yl]-2-butenoic Acid; Chiral Terpenoid Acid Intermediate
EINECS	Contact for details

Quality Control

Our (E)-3-[(R)-4-Methyl-3-Cyclohexen-1-Yl]-2-Butenoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC and structural confirmation by NMR and IR spectroscopy, to ensure high chemical and enantiomeric purity. Certificates of Analysis (COA) with detailed specifications are provided for each shipment to guarantee batch-to-batch consistency and traceability for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents and bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.