Description

p-Hydroxybiphenylacetic Acid (CAS NO 51350-23-3) is a high-value biphenyl derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both phenolic and acetic acid functionalities, makes it a versatile building block for constructing complex molecules. This compound is essential for manufacturers and R&D teams in the pharmaceutical and fine chemical sectors seeking to develop novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs) and other active pharmaceutical ingredients (APIs).
• Liquid Crystal Material Synthesis: Serves as a core building block for creating biphenyl-based mesogens used in display technologies.
• Organic Electronic Materials: Used in the development of charge-transport materials and organic semiconductors.
• Agrochemical Synthesis: Intermediate for producing advanced herbicides and plant growth regulators with specific activity.
• Polymer Modification: Functional monomer for introducing phenolic groups into polymer chains to alter thermal and chemical properties.
• Research & Development: Valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	p-Hydroxybiphenylacetic Acid
CAS No.	51350-23-3
Molecular Formula	C₁₄H₁₂O₃
Molecular Weight	228.24 g/mol
Synonyms	4-(4-Hydroxyphenyl)phenylacetic Acid; 4'-Hydroxybiphenyl-4-acetic Acid; 4-(4-Hydroxyphenyl)benzeneacetic Acid; [1,1'-Biphenyl]-4-acetic acid, 4'-hydroxy-; p-Hydroxydiphenylacetic Acid; 4'-Hydroxy-4-biphenylacetic Acid; (4'-Hydroxy[1,1'-biphenyl]-4-yl)acetic Acid
EINECS	Contact for details

Quality Control

Our p-Hydroxybiphenylacetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the stringent requirements of our global clientele. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere for long-term storage). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	205°C - 210°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.