Description

2-Amino-2-Benzyl-3-Hydroxypropanoic Acid is a chiral non-proteinogenic amino acid derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both amino and hydroxy functional groups on a phenylalanine-like backbone, makes it a versatile intermediate for constructing complex molecules with high stereochemical control. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing peptide mimetics, enzyme inhibitors, and novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, including protease inhibitors and other biologically active molecules.
• Peptidomimetics Research: Used to design and synthesize peptide analogs with enhanced metabolic stability and bioavailability for therapeutic applications.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in stereoselective reactions to introduce specific configurations into target molecules.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies to investigate metabolic pathways and enzyme mechanisms.
• Fine Chemical Production: A valuable intermediate in the multi-step synthesis of complex specialty chemicals, flavors, and fragrances.
• Ligand Development: Used in the preparation of chiral ligands for catalysis, aiding in the development of more efficient and selective synthetic processes.

Basic Information

Product Name	2-Amino-2-Benzyl-3-Hydroxypropanoic Acid
CAS No.	51127-30-1
Molecular Formula	C10H13NO3
Molecular Weight	195.22 g/mol
Synonyms	2-Amino-2-benzyl-3-hydroxypropanoic acid; 2-Benzylserine; (R,S)-2-Benzylserine; (±)-2-Benzylserine; 3-Hydroxy-2-(phenylmethyl)alanine; 2-Amino-3-hydroxy-2-phenylmethylpropionic acid; DL-2-Benzylserine; α-Benzylserine
EINECS	Contact for details

Quality Control

Our 2-Amino-2-Benzyl-3-Hydroxypropanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the high standards required for research and pharmaceutical development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.