Description

Piperidin-3-yl trifluoromethanesulfonate is a versatile triflate ester derivative of 3-piperidinol, serving as a key building block in advanced organic synthesis. This compound is particularly valued for its role as a reactive intermediate in the formation of carbon-nitrogen and carbon-carbon bonds under mild conditions. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A critical synthon for the construction of piperidine-containing drug candidates, including kinase inhibitors, CNS-active compounds, and antiviral agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that incorporate the piperidine scaffold for enhanced biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing nitrogen-containing ligands for transition metal catalysis and organocatalysts.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with specific electronic or structural properties.
• Custom Chemical Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects and scale-up development.

Basic Information

Product Name	Piperidin-3-yl Trifluoromethanesulfonate
CAS No.	51036-12-5
Molecular Formula	C6H10F3NO3S
Molecular Weight	233.21 g/mol
Synonyms	3-Piperidinol, 1,1,1-trifluoro-N-(3-piperidinyl)methanesulfonate; 3-(Trifluoromethanesulfonyloxy)piperidine; 1,1,1-Trifluoro-N-(3-piperidinyl)methanesulfonamide; 3-Piperidyl Triflate; 3-Hydroxypiperidine Triflate; Piperidin-3-ol Trifluoromethanesulfonate; 3-Triflyloxypiperidine
EINECS	Contact for details

Quality Control

Every batch of Piperidin-3-yl Trifluoromethanesulfonate is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure product identity, purity, and consistency for your critical research and development work. A Certificate of Analysis (COA) detailing specifications such as assay (HPLC), identity (IR, NMR), and impurity profiles is available with each shipment and upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Individual Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.